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Diagnostics

Skin biopsy

Skin biopsy provides tissue for histopathological examination and supports definitive diagnosis.

Published: Feb 14, 2026 · Updated: Feb 14, 2026

Skin lesion selected for biopsy

What skin biopsy is

Skin biopsy is a diagnostic procedure in which part or all of a lesion is collected for histopathological analysis.

When biopsy is used

Biopsy is considered when clinical and dermoscopic evaluation suggests that microscopic confirmation is needed before treatment decisions.

Common techniques

  • incisional biopsy (sample of a larger lesion),
  • punch biopsy (small circular sample or complete removal of a small lesion).

Why histopathology matters

Histopathology remains the key method for final diagnosis and helps define the most appropriate next therapeutic step.

Medical information

This content is informational and does not replace an individual medical consultation or histopathological diagnostics.

Frequently asked questions

Is a biopsy painful?

The procedure is usually performed under local anesthesia, so discomfort is limited.

Why is histopathology required?

Histopathology confirms lesion type and supports further treatment planning.